Prognosis for Peritoneal Mesothelioma
The prognosis for peritoneal mesothelioma depends on:
Stage at diagnosisTumor grade (how fast it grows)
GenderGenetic mutationsTreatments selected
The rate of cancer progression is highly variable in this type of mesothelioma. It is hard to predict individual prognosis.
In the ’80s and ’90s, average survival time was around one year. Today, more people are living longer with this disease. Survival is significantly longer for patients who qualify for surgery with heated chemotherapy. Nearly half of these patients live longer than five years.
More than 60 percent of patients are diagnosed too late to qualify for surgery. These patients often elect chemotherapy. The combination of cisplatin and pemetrexed delivered systemically has a response rate around 30 percent with average progression-free survival around 11.5 months and median survival around 13 months.
Chemotherapy delivered directly, not systemically, to the peritoneum without surgery has a higher response rate of 47 percent. Meanwhile, heated chemotherapy delivered during surgery has a response rate of 84.6 percent.
Women tend to live longer with peritoneal mesothelioma than men. When short- and long-term survival is averaged out, women live an average of 13 months, and men live six months.
The median survival of untreated peritoneal mesothelioma is six months.
Patients with tumors containing epithelial cells live longer than patients with sarcomatoid or biphasic cells. The tumor’s grade also impacts prognosis. Tumor grade is based upon how abnormal the cells appear, which indicates how quickly they are likely to grow and spread.
HALAMAN SELANJUTNYA:
